Gabapentin for Anxiety Benefits, Dosage, and Side Effects


Gabapentin is a prescription medication that was originally used to treat seizures and nerve pain. Eventually, doctors found that gabapentin may offer benefits for certain mental health conditions, like anxiety. Gabapentin is not FDA-approved for treating anxiety; however, many healthcare providers prescribe it off-label due to its lack of effectiveness compared to first-line medications.

How Gabapentin Helps with Anxiety 

Anxiety disorders are commonly characterized by excessive worry, tension, and physical discomfort. While SSRIs (antidepressants) and benzodiazepines can be effective for anxiety, they don't work for everyone. 

Gabapentin is not act on serotonin or dopamine. Instead, gabapentin targets calcium channels in the brain. When the calcium channels are blocked, it dulls the transmission of exciting neurons, alleviating the excess nerve signals and allowing the nervous system to relax. Said differently, gabapentin slows the brain signals that trigger stress and worry. 

Gabapentin Dosage for Anxiety 

The correct dose for gabapentin depends on each person's health status and their response to gabapentin. Most providers start with a low dose of 100–300 mg of gabapentin daily and increase the dose accordingly. 



The common dosages for patients being prescribed gabapentin for anxiety is around 900 – 1800 mg per day divided into smaller doses. Only a licensed medical provider is able to establish patients' individual safest amount for their treatment. 

Gabapentin for Insomnia and Anxiety

Many individuals with anxiety also have insomnia. Gabapentin can treat both conditions. Research shows that gabapentin can 

Reduce the time it takes to fall asleep

Reduce the number of awakenings during the night

Improve overall sleep quality

Gabapentin may help both emotionally and with sleep by suppressing the nervous system.

Common Side Effects of Gabapentin

Like other drugs, there can be side effects. Common ones include:

  • Drowsiness or dizziness
  • Tiredness
  • Weight gain
  • Coordination issues
  • Blurred vision

Some individuals may feel more anxious or moody while starting the new medication, or changing doses. There are also serious effects, but rare ones that can happen too. Because of this, always be under medical supervision while taking gabapentin.

Conclusion

Gabapentin should not be considered a first-line treatment of anxiety, however, can help individuals who do not get relief from other medications. If you are interested in gabapentin, talk to your physician about whether this is a good option for you, including the benefits and risks.

Interested in learning more? Read the full in-depth guide here.


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