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Gabapentin is a prescription medication that was originally used to treat seizures and nerve pain. Eventually, doctors found that gabapentin may offer benefits for certain mental health conditions, like anxiety. Gabapentin is not FDA-approved for treating anxiety; however, many healthcare providers prescribe it off-label due to its lack of effectiveness compared to first-line medications. How Gabapentin Helps with Anxiety  Anxiety disorders are commonly characterized by excessive worry, tension, and physical discomfort. While SSRIs (antidepressants) and benzodiazepines can be effective for anxiety, they don't work for everyone.  Gabapentin is not act on serotonin or dopamine. Instead, gabapentin targets calcium channels in the brain. When the calcium channels are blocked, it dulls the transmission of exciting neurons, alleviating the excess nerve signals and allowing the nervous system to relax. Said differently, gabapentin slows the brain signals that trigger stress and worry...

Baclofen is an FDA approved, prescription medication that is widely prescribed for muscle stiffness , and spasms, and spasticity. It comes in 5 mg, 10 mg, and 20 mg tablets, and is typically prescribed for persons with MS, spinal cord injuries, or chronic muscle pain. Baclofen works on the spinal cord nerves and blocks tight muscles, spasms, and spasticity, which can improve ease of accomplishment for daily tasks. When to Think About Baclofen You may want to consider using Baclofen if you have continuous muscle tightness or spasms that are painful to you. Baclofen works particularly well for spasms associated with MS; it can decrease the intensity of involuntary contractions and also decrease the frequency of these contractions. Baclofen dosing The dosing of Baclofen is dependent upon your medical condition and how your body tolerates the medication. Typical dosing recommendations are as follows:  1) Starting dose (not to exceed): 5 mg (three times a day);  2) Intermediate do...